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Woman at home in warm morning light
Alumei HRT Cream metered-pump bottle, net wt. 1.76 oz
Feel Like Yourself Again

Hormone therapy, simplified for perimenopause and menopause.

  • Physician-prescribed estradiol and progesterone in one convenient vaginal cream
  • Designed to simplify hormone therapy — 10-second daily routine
  • Address hot flashes, poor sleep, vaginal dryness, mood changes, brain fog and more
Start your online visit →

Takes about 5–10 minutes. No office visit required. Prescription treatment is provided only when medically appropriate.

Two hormones One nightly routine Licensed-provider review Delivered every 90 days
Licensed-provider review
Licensed U.S. pharmacy
Discreet shipping
HSA/FSA eligible
You're Not Imagining It

Real symptoms. Real shifts. A real reason to ask what is changing.

  • Hot flashes
  • Restless nights
  • Vaginal dryness
  • Mood changes
  • Brain fog
  • Fatigue

If you've been feeling unlike yourself, hormonal changes during perimenopause or menopause may be part of the picture.

These changes can show up differently for every woman. The point isn't to self-diagnose — it's to be heard and have your symptoms reviewed by a licensed provider.

Alumei metered-pump cream bottle on a ceramic surface with a cream swatch
A Simpler Routine

Two hormones. One nightly routine.

Alumei is a compounded prescription vaginal cream that combines estradiol and progesterone in one metered-pump formulation. If prescribed, your provider determines the appropriate formulation and daily amount based on your medical intake.

Estradiol + progesterone

Two hormones together in one prescription cream.

Metered pump

A consistent, measured amount with every use — no guessing.

One prescribed routine

Designed to fit easily into your evening.

Delivered every 90 days

Shipped discreetly on a 90-day cycle.

You won't choose a dose. A licensed provider determines the appropriate formulation and daily amount after reviewing your medical intake.

Prescription treatment is available only when medically appropriate.

Perimenopause and menopause can feel different. Your next step can be the same.

Woman in her late forties in a natural, relaxed setting

Perimenopause Finding balance through change.

Cycles may still be changing. Symptoms can appear before periods stop completely. Tell us what you're experiencing, your health history, and your goals.

Woman in her late fifties enjoying a calm morning at home

Menopause A new chapter, with support.

After periods have stopped, symptoms can continue or change. Your provider reviews your intake to determine whether hormone therapy may be medically appropriate.

You do not choose your own hormone dose. A licensed provider determines the appropriate formulation and daily amount after clinical review.

How It Works

Care that fits your life.

A simple online process — from your home to your door.

Woman completing her online intake on her phone at home
1

Tell us how you're feeling

Complete a short online intake about your symptoms, health history and goals. Takes about 5–10 minutes.

Licensed provider reviewing a patient intake at a laptop
2

Licensed-provider review

A licensed provider reviews your intake and determines whether hormone therapy is medically appropriate.

Prescription being prepared for the pharmacy
3

Prescription, if appropriate

If prescribed, your provider determines the formulation and daily amount. Your prescription is sent to the pharmacy.

Discreet delivery package with the Alumei box
4

Delivered to your door

Your medication is prepared and shipped discreetly. Current fulfillment is every 90 days.

— available through the clinical care team and secure chat.

The Stats

Measured improvements in just a few weeks.

In a 6-month outcomes review of women using Alumei. These changes reflect restored hormone levels — not temporary symptom masking.

0%

improved vaginal dryness

0%

improved sleep quality

0%

improved mood

0%

sharper focus & vitality

0%

improved energy levels

Macro detail of the Alumei cream texture
The Formula

Thoughtfully formulated. Reviewed by a licensed provider.

Alumei is a compounded prescription cream that combines estradiol and progesterone in an Ellage® anhydrous vaginal base.

Hormone therapy can involve different formulations and delivery methods. Different options have different benefits, limitations and patient considerations — your licensed provider can help determine what is appropriate for you.

Estradiol

One of the active hormones in Alumei.

Progesterone

One of the active hormones in Alumei.

Ellage® base

The anhydrous base used to compound the cream.

Your prescribed formulation and daily amount are determined after clinical review.

Inside the Formula

Every ingredient, explained.

E26 mg/gm

Bioidentical estradiol

The most potent of the body's estrogens — and the one that declines most sharply through menopause. Restoring estradiol supports:

Bioidentical estradiol

  • Hot flashes & night sweats — the classic vasomotor symptoms
  • Vaginal & urinary health — elasticity, lubrication, comfort during intimacy
  • Bone density — estrogen is central to bone strength
  • Mood & cognition — many women report clearer thinking
  • Skin & sleep — collagen support, fewer 3 a.m. wake-ups
P4200 mg/gm

Micronized progesterone

Estrogen's essential partner — protective, calming, and dosed to reflect the body's own physiology.

Micronized progesterone

  • Endometrial protection — balances estrogen's effect on the uterine lining
  • Sleep support — its metabolites act on GABA, the brain's calming pathway
  • Calm & mood — often called the "quieting" hormone
  • Symptom stability — smooths perimenopause's hormonal turbulence

"Micronized" means the particles are ultra-fine for better absorption. The higher dose vs. estradiol is intentional — it mirrors the body's natural ratio.

BaseEllage®

Ellage® anhydrous base

The first water-free base developed specifically for vaginal medication — and what sets Alumei apart from ordinary creams.

Ellage® anhydrous base

  • Self-emulsifying delivery — forms a micro-emulsion on contact with natural moisture, releasing hormones directly to the tissue
  • Mucoadhesive = less leakage — holds hormones in contact with tissue; in vitro testing shows significant potential to minimize leakage
  • Gentle — published in vitro studies show it's nonirritating and doesn't affect vaginal pH
  • Works even with dryness — self-emulsifies with only trace moisture

Formulated without wheat, gluten, milk, egg, soy, fish/crustacean, peanut, or tree nuts.

Pricing & Membership

One treatment. One price. Everything included.

50 mL bottle3-month supply Hand holding the Alumei HRT Cream metered-pump bottle

One simple treatment.

$179/month
  • Billed monthly — each shipment is one 50 mL bottle containing a 3-month supply, delivered every 90 days
  • Both prescription strengths — same price, same one-pump nightly routine
  • Physician review, dose adjustments, chat support and free discreet shipping included
  • No insurance needed. No contracts or cancellation fees
Start your online visit →

Prescription required. Your strength is determined by a licensed physician after clinical review. If treatment isn't prescribed, you won't be charged for medication.

A simpler way to start the conversation about HRT.

Tell us what you're experiencing. A licensed provider will review your health history and determine whether prescription treatment is medically appropriate.

Start your online visit →

Takes about 5–10 minutes. No office visit required.

Frequently asked questions.

What is Alumei™?

Alumei is a compounded prescription vaginal cream that combines estradiol and progesterone. It is available only when prescribed by a licensed healthcare provider after clinical evaluation.

Do I choose my strength or dose?

No. You'll tell us about your symptoms, medical history and goals. A licensed provider determines whether treatment is appropriate and, if so, the formulation and daily amount.

How does the online visit work?

Complete a short online intake about your symptoms and health history. A licensed provider reviews it and may contact you through the secure portal if more information is needed. If treatment is medically appropriate and prescribed, the prescription is sent to the pharmacy.

How often is Alumei delivered?

If prescribed, Alumei is currently dispensed on a 90-day delivery cycle.

What support is available after I start?

Patients have access to the clinical care team and secure chat for questions and ongoing support.

Is Alumei FDA-approved?

Alumei is a compounded prescription medication and is not FDA-approved. Compounded medications are prepared by licensed pharmacies based on a prescriber's order. The FDA does not verify the safety, effectiveness or quality of compounded drugs.