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★★★★★ 4.8/5 from trusted reviews

Lose Up to 22% of Your Body Weight

Clinician-guided weight loss with compounded semaglutide or tirzepatide — weekly injection or daily oral tablet, delivered to your door. Overnight shipping!

Starting at $145/mo 2-minute online assessment

  • 100% online medical visit
  • No insurance required
  • Licensed U.S. providers
  • Overnight shipping
Woman feeling confident and energized after weight loss
No Hidden Fees
No Membership
Cancel Anytime

What GLP-1 Can Help With

A clinically guided path to steady, sustainable weight loss

GLP-1 medications work with your body's own appetite signals to help you eat less, feel full sooner, and lose weight gradually — under the supervision of a licensed provider. Here's what they may help with.

Appetite Regulation

Help quiet constant hunger and "food noise" so you feel satisfied with smaller portions throughout the day.

Fewer Cravings

Support better control over cravings and snacking between meals, making healthier choices easier to stick with.

Steady, Sustainable Progress

Many patients lose up to 1.5% of their body weight per week alongside diet and lifestyle changes.

BetterMe Rx Compounded GLP-1 vial Compounded with glycine

Slower Gastric Emptying

GLP-1s slow how quickly your stomach empties, helping you stay fuller longer after each meal.

Blood-Sugar Support

Help your body manage blood sugar and how it converts food into usable energy.

Provider-Guided Dosing

A licensed U.S. provider tailors your dose and checks in — not a one-size-fits-all program.

Trusted By 250,000+ Patients served nationwide
Average Results Up to 22% Body weight lost*
No Clinic Visits 100% Online Treatment from home
Trusted Care U.S. Licensed Providers & pharmacies

Real Patient Experiences

What people are saying about GLP-1 with BetterMe Rx

There's no shame in getting support for your weight. Combined with healthy habits, GLP-1 therapy can be part of feeling lighter, more confident, and in control.

★★★★★

The hunger finally quieted

For the first time, I'm not thinking about food all day. Portions that used to feel small now leave me satisfied.

— Cassandra K.
★★★★★

Steady, real progress

A few pounds a week, consistently. Nothing drastic — just sustainable progress I can actually keep up with.

— Brenda R.
★★★★★

So much easier than I expected

The whole thing was online and simple. My provider adjusted my dose and the tablets arrived right to my door.

— Pier A.
★★★★★

More confident every week

My clothes fit better and I have more energy. I feel like myself again — and the check-ins keep me on track.

— Missel M.
★★★★★

No insurance headaches

One simple monthly price, no pharmacy runaround, no denials. It just shows up. That alone was worth it.

— Sheri M.
★★★★★

The pill option sold me

I didn't want needles, so the daily tablet was perfect. Easy to take and I'm seeing results.

— Anna B.

Fast & Simple

Get your GLP-1 in just 1-2 days

Weight-loss care without the long waits or clinic visits. Here's the path from start to your first dose.

1

Answer a few questions

A quick, confidential online health intake — about one minute.

2

Provider review

A licensed U.S. provider reviews your chart, usually within 24 hours.

3

Pharmacy fills it

If appropriate, your prescription ships from a U.S.-based pharmacy.

4

Delivered to you

Free, discreet delivery — everything you need to get started included.

5

Ongoing support

Track progress and adjust your dose with continued provider care.

Person walking outdoors, feeling lighter and more energized

Working With Your Body, Not Against It

What happens when hunger finally works with you?

For many people, weight isn't about willpower — it's about biology. Constant hunger and cravings make it hard to sustain any plan, no matter how disciplined you are.

GLP-1 medications help regulate the appetite signals between your gut and brain, so you feel full sooner and stay satisfied longer. Paired with healthy habits, that can make steady, lasting weight loss feel achievable — often for the first time.

Know What You're Getting

Not all weight-loss programs are the same

Be cautious of one-size-fits-all programs and unverified sources. BetterMe Rx offers compounded GLP-1 from licensed U.S. providers and pharmacies — oral or injectable.

BetterMe Rx
Compounded GLP-1
Name-Brand GLP-1 Other Online Clinics
Oral & injectable optionsYes — both formsUsually injection onlyOften limited
Provider review includedYes — U.S.-licensedSeparate appointmentVaries
Compounded with glycineYes (injectables)N/AVaries
Starting costFrom $145/mo$1,000+/mo cash$$$
Insurance requiredNoOften — and frequently deniedVaries
Delivered to your doorFree & discreetPharmacy pickupVaries

Comparison is for general education. Treatment is provided only if deemed medically appropriate by a licensed provider.

Limited-time intro pricing

GLP-1 weight loss from $145/mo

Save up to 48% off retail with an annual plan — semaglutide & tirzepatide, oral or injectable. Ships free in 1–2 days.

Claim your intro price

Simple, All-Inclusive Pricing

Choose your GLP-1

Every plan includes your medication, provider review, pharmacy compounding, supplies & free shipping.

Most Affordable BetterMe Rx Compounded Semaglutide injection vial

Semaglutide Injection

Weekly shot · compounded w/ glycine

$279$205/mo

as low as $145/mo on the 12-mo plan · cancel anytime

Save up to 48% Start Free Evaluation
★ Most Effective BetterMe Rx Compounded Tirzepatide injection vial

Tirzepatide Injection

Weekly shot · compounded w/ glycine

$379$275/mo

as low as $215/mo on the 12-mo plan · cancel anytime

Save up to 43% Start Free Evaluation
BetterMe Rx Compounded Semaglutide oral tablet

Semaglutide Oral+

Needle-free · daily tablet

$299$250/mo

as low as $185/mo on the 12-mo plan · cancel anytime

Save up to 38% Start Free Evaluation
BetterMe Rx Compounded Tirzepatide oral tablet

Tirzepatide Oral

Needle-free · daily tablet

$399$265/mo

as low as $215/mo on the 12-mo plan · cancel anytime

Save up to 46% Start Free Evaluation

Prices shown are per month. Longer supply plans (3, 6, or 12 months) lock in a lower per-month price and are billed per your selected plan. Treatment is provided only if deemed medically appropriate by a licensed provider. If your prescription isn't approved, you won't be charged for the medication.

We've Got You

Frequently asked questions

How does BetterMe Rx work?
BetterMe Rx makes it easy to access prescription GLP-1 weight-loss treatment from home. Your simple price includes the medication, supplies, provider review, and shipping — no insurance needed. Complete a short intake form, and once a licensed provider reviews and approves it, your prescription is filled by a U.S.-based pharmacy and shipped to your door. When you're ready to reorder, log into your patient portal to request a refill.
How do I take semaglutide or tirzepatide?
Oral tablets (semaglutide or tirzepatide): Take one tablet daily by mouth with water, ideally at the same time each day. Follow the dosing instructions from your pharmacy and prescribing provider, and avoid eating for 30–60 minutes after your dose unless otherwise directed.

Injectable (semaglutide or tirzepatide): Inject subcutaneously (under the skin) once weekly, on the same day each week — into the stomach, thigh, or upper arm. Rotate injection sites to avoid irritation, and do not inject into muscle or vein.
What should I do if I miss a dose?
Oral tablets: Take it as soon as you remember — unless it's been more than 24 hours. If it's close to your next dose, skip the missed one and return to your regular schedule. Do not double up.

Injectable: If it's been less than 4 days, take it as soon as possible. If more than 4 days have passed, skip the missed dose and resume your regular weekly schedule. Do not take two injections within 3 days of each other.
How should I store my medication?
Oral tablets: Store at room temperature in a cool, dry place away from heat, light, and moisture. Keep tablets in their original container with the lid tightly closed.

Injectable: Keep refrigerated (36–46°F) and protect from light. Do not freeze. Some compounded versions may be stored at room temperature for a limited time once opened — follow your pharmacy's storage guidelines closely.
How does pricing work?
BetterMe Rx works with licensed U.S. providers and U.S.-based compounding pharmacies to keep GLP-1 treatment affordable, with clear, all-inclusive pricing. Every plan includes your medication, provider review, pharmacy compounding, supplies, and free shipping — no hidden fees.
  • Semaglutide Injection: $205/mo on the 1-month plan, as low as $145/mo on a 12-month plan.
  • Tirzepatide Injection: $275/mo on the 1-month plan, as low as $215/mo on a 12-month plan.
  • Semaglutide Oral+ (tablet): $250/mo on the 1-month plan, as low as $185/mo on a 12-month plan.
  • Tirzepatide Oral (tablet): $265/mo on the 1-month plan, as low as $215/mo on a 12-month plan.

Your plan renews so your treatment never lapses, and you can cancel anytime from your BetterMe Rx Patient Portal. Choosing a longer supply plan simply locks in a lower monthly price.

When will I see results?
Results vary from person to person. Clinical studies have shown an average of 16% total body weight loss with semaglutide and 22% with tirzepatide when combined with lifestyle changes such as diet and exercise, with some individuals losing up to 1.5% of their body weight per week. Many people begin to notice changes in appetite within the first few weeks, while weight loss builds gradually with consistent use. Following your provider's protocol matters, and BetterMe Rx does not guarantee individual results.
Can I continue my current dose if I'm switching from another provider?
Yes, but only under medical supervision. If you've already been prescribed a specific dose of semaglutide or tirzepatide, your assigned clinician will review your medical history and current dosage to determine if continuation is appropriate. In most cases we can resume treatment at the same or an adjusted dose, depending on the formulation and your clinical profile. Be prepared to share recent health information and records of your current treatment when completing your intake.

Ready When You Are

Ready to reach your goal weight?

It starts with a few simple questions. See if clinician-guided GLP-1 is right for you — from the comfort of home.